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Sperm acrosome overgrowth and infertility in mice lacking chromosome 18 pachytene piRNA

piRNAs are small non-coding RNAs required to maintain genome integrity and preserve RNA homeostasis during male gametogenesis. In murine adult testes, the highest levels of piRNAs are present in the pachytene stage of meiosis, but their mode of action and function remain incompletely understood. We...

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Veröffentlicht in:PLoS Genet
Hauptverfasser: Choi, Heejin, Wang, Zhengpin, Dean, Jurrien
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8057611/
https://ncbi.nlm.nih.gov/pubmed/33831001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009485
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