Population pharmacokinetic analysis of peficitinib in patients with rheumatoid arthritis

AIMS: To analyse the population pharmacokinetics (PK) of peficitinib in patients with rheumatoid arthritis (RA) and assess the potential PK covariates to identify the requirement for dose adjustment in RA patients. METHODS: The analysis incorporated 2464 observations from 98 healthy volunteers and 4...

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Publicado en:Br J Clin Pharmacol
Autores principales: Toyoshima, Junko, Shibata, Mai, Kaibara, Atsunori, Kaneko, Yuichiro, Izutsu, Hiroyuki, Nishimura, Tetsuya
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8056739/
https://ncbi.nlm.nih.gov/pubmed/33068028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14605
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