Pharmacokinetics and Safety of a Single Oral Dose of Peficitinib (ASP015K) in Japanese Subjects with Normal and Impaired Renal Function

BACKGROUND AND OBJECTIVE: This study measured and compared the exposure and safety of peficitinib (ASP015K), a novel oral Janus kinase inhibitor, in subjects with normal and impaired renal function after a single oral, clinically relevant peficitinib dose. METHODS: This was an open-label, parallel-g...

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Publicat a:Clin Drug Investig
Autors principals: Miyatake, Daisuke, Shibata, Tomohisa, Shibata, Mai, Kaneko, Yuichiro, Oda, Kazuo, Nishimura, Tetsuya, Katashima, Masataka, Sekino, Hisakuni, Furihata, Kenichi, Urae, Akinori
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2019
Matèries:
Original Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989572/
https://ncbi.nlm.nih.gov/pubmed/31729626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40261-019-00873-7
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