Transcriptomic profiling of three-dimensional cholangiocyte spheroids long term exposed to repetitive Clonorchis sinensis excretory-secretory products

BACKGROUND: Biliary tract infection with the carcinogenic human liver fluke, Clonorchis sinensis, provokes chronic inflammation, epithelial hyperplasia, periductal fibrosis, and even cholangiocarcinoma. Complications are proportional to the intensity and duration of the infection. In addition to mec...

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Bibliographic Details
Published in:Parasit Vectors
Main Authors: Kim, Jung-Woong, Yi, Junyeong, Park, Jinhong, Jeong, Ji Hoon, Kim, Jinho, Won, Jihee, Chung, Seok, Kim, Tong-Soo, Pak, Jhang Ho
Format: Artigo
Language:Inglês
Published: BioMed Central 2021
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8056535/
https://ncbi.nlm.nih.gov/pubmed/33879231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-021-04717-2
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