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Transcriptomic profiling of three-dimensional cholangiocyte spheroids long term exposed to repetitive Clonorchis sinensis excretory-secretory products

BACKGROUND: Biliary tract infection with the carcinogenic human liver fluke, Clonorchis sinensis, provokes chronic inflammation, epithelial hyperplasia, periductal fibrosis, and even cholangiocarcinoma. Complications are proportional to the intensity and duration of the infection. In addition to mec...

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Vydáno v:Parasit Vectors
Hlavní autoři: Kim, Jung-Woong, Yi, Junyeong, Park, Jinhong, Jeong, Ji Hoon, Kim, Jinho, Won, Jihee, Chung, Seok, Kim, Tong-Soo, Pak, Jhang Ho
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8056535/
https://ncbi.nlm.nih.gov/pubmed/33879231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-021-04717-2
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