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Inhibition of DKC1 induces telomere-related senescence and apoptosis in lung adenocarcinoma

BACKGROUND: Lung cancer is one of the most widely spread cancers in the world and half of the non-small cell lung cancers are lung adenocarcinoma (LUAD). Although there were several drugs been approved for LUAD therapy, a large portion of LUAD still cannot be effectively treated due to lack of avail...

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Détails bibliographiques
Publié dans:J Transl Med
Auteurs principaux: Kan, Guangyan, Wang, Ziyang, Sheng, Chunjie, Yao, Chen, Mao, Yizhi, Chen, Shuai
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2021
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8056518/
https://ncbi.nlm.nih.gov/pubmed/33879171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-021-02827-0
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