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Analysis of BRCA1/2 variants of unknown significance in the prospective Korean Hereditary Breast Cancer study

Genetic testing for BRCA1 and BRCA2 is crucial in diagnosing hereditary breast and ovarian cancer syndromes and has increased with the development of multigene panel tests. However, results classified as variants of uncertain significance (VUS) present challenges to clinicians in attempting to choos...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kim, Joo Heung, Park, Sunggyun, Park, Hyung Seok, Park, Ji Soo, Lee, Seung-Tae, Kim, Sung-Won, Lee, Jong Won, Lee, Min Hyuk, Park, Sue K., Noh, Woo-Chul, Choi, Doo Ho, Han, Wonshik, Jung, Sung Hoo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8055990/
https://ncbi.nlm.nih.gov/pubmed/33875706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-87792-w
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