Inhibition of Acyl-CoA Synthetase Long-Chain Family Member 4 Facilitates Neurological Recovery After Stroke by Regulation Ferroptosis

BACKGROUND: Ischemic stroke is the main cause of disability worldwide, leading to a serious socioeconomic burden. Ferroptosis is a non-apoptotic form of programmed cell death and is related to various diseases. Acyl-CoA synthetase long-chain family member 4 (ACSL4) is considered a target of ferropto...

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Veröffentlicht in:Front Cell Neurosci
Hauptverfasser: Chen, Junmin, Yang, Lan, Geng, Lianxia, He, Junna, Chen, Lei, Sun, Qian, Zhao, Jing, Wang, Xiaopeng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8055945/
https://ncbi.nlm.nih.gov/pubmed/33889074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2021.632354
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