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Curcumin activates Nrf2 through PKCδ-mediated p62 phosphorylation at Ser351
Curcumin, a phytochemical extracted from Curcuma longa rhizomes, is known to be protective in neurons via activation of Nrf2, a master regulator of endogenous defense against oxidative stress in cells. However, the exact mechanism by which curcumin activates Nrf2 remains controversial. Here, we obse...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8055680/ https://ncbi.nlm.nih.gov/pubmed/33875681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-87225-8 |
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