TFEB activates Nrf2 by repressing its E3 ubiquitin ligase DCAF11 and promoting phosphorylation of p62

Transcriptional factor EB (TFEB) and nuclear factor E2-related factor 2 (Nrf2) play crucial roles in the biological response against cellular stressors; however, their relationship has not yet been investigated. Here, we constructed human neuroglioma cell lines stably expressing TFEB. The expression...

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Gepubliceerd in:Sci Rep
Hoofdauteurs: Park, Jee-Yun, Kim, Sunhyo, Sohn, Hee Young, Koh, Young Ho, Jo, Chulman
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778067/
https://ncbi.nlm.nih.gov/pubmed/31586112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50877-8
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