VEGFR-1/Flt-1 inhibition increases angiogenesis and improves muscle function in a mouse model of Duchenne muscular dystrophy

Duchenne muscular dystrophy is characterized by structural degeneration of muscle, which is exacerbated by localized functional ischemia due to loss of nitric oxide synthase-induced vasodilation. Treatment strategies aimed at increasing vascular perfusion have been proposed. Toward this end, we have...

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Опубликовано в: :Mol Ther Methods Clin Dev
Главные авторы: Bosco, Jennifer, Zhou, Zhiwei, Gabriëls, Sofie, Verma, Mayank, Liu, Nan, Miller, Brian K., Gu, Sheng, Lundberg, Dianna M., Huang, Yan, Brown, Eilish, Josiah, Serene, Meiyappan, Muthuraman, Traylor, Matthew J., Chen, Nancy, Asakura, Atsushi, De Jonge, Natalie, Blanchetot, Christophe, de Haard, Hans, Duffy, Heather S., Keefe, Dennis
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Gene & Cell Therapy 2021
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8055526/
https://ncbi.nlm.nih.gov/pubmed/33898634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2021.03.013
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