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Kidney Tissue Hypoxia Dictates T-Cell Mediated Injury in Murine Lupus Nephritis

The kidney is a frequent target of autoimmune injury, including in systemic lupus erythematosus; however, how immune cells adapt to kidney’s unique environment and contribute to tissue damage is unknown. We found that renal tissue, which normally has low oxygen tension, becomes more hypoxic in lupus...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Sci Transl Med
Κύριοι συγγραφείς: Chen, Ping-Min, Wilson, Parker C., Shyer, Justin A., Veselits, Margaret, Steach, Holly R., Cui, Can, Moeckel, Gilbert, Clark, Marcus R., Craft, Joe
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2020
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8055156/
https://ncbi.nlm.nih.gov/pubmed/32269165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aay1620
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