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Kidney Tissue Hypoxia Dictates T-Cell Mediated Injury in Murine Lupus Nephritis
The kidney is a frequent target of autoimmune injury, including in systemic lupus erythematosus; however, how immune cells adapt to kidney’s unique environment and contribute to tissue damage is unknown. We found that renal tissue, which normally has low oxygen tension, becomes more hypoxic in lupus...
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| Publicado no: | Sci Transl Med |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8055156/ https://ncbi.nlm.nih.gov/pubmed/32269165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aay1620 |
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