A Non-Canonical Type 2 Immune Response Coordinates Tuberculous Granuloma Formation and Epithelialization

The central pathogen-immune interface in tuberculosis is the granuloma, a complex host immune structure that dictates infection trajectory and physiology. Granuloma macrophages undergo a dramatic transition in which entire epithelial modules are induced and define granuloma architecture. In tubercul...

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Pubblicato in:Cell
Autori principali: Cronan, Mark R., Hughes, Erika J., Brewer, W. Jared, Viswanathan, Gopinath, Hunt, Emily G., Singh, Bindu, Mehra, Smriti, Oehlers, Stefan H., Gregory, Simon G., Kaushal, Deepak, Tobin, David M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8055144/
https://ncbi.nlm.nih.gov/pubmed/33761328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2021.02.046
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