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Transcriptional Reprogramming in Nonhuman Primate (Rhesus Macaque) Tuberculosis Granulomas

BACKGROUND: In response to Mtb infection, the host remodels the infection foci into a dense mass of cells known as the granuloma. The key objective of the granuloma is to contain the spread of Mtb into uninfected regions of the lung. However, it appears that Mtb has evolved mechanisms to resist kill...

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Main Authors: Mehra, Smriti, Pahar, Bapi, Dutta, Noton K., Conerly, Cecily N., Philippi-Falkenstein, Kathrine, Alvarez, Xavier, Kaushal, Deepak
格式: Artigo
語言:Inglês
出版: Public Library of Science 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930844/
https://ncbi.nlm.nih.gov/pubmed/20824205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012266
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