PLCδ1 Plays Central Roles in the Osmotic Activation of ΔN-TRPV1 Channels in Mouse Supraoptic Neurons and in Murine Osmoregulation

The magnocellular neurosecretory cells (MNCs) of the hypothalamus play a vital role in osmoregulation, but the mechanisms underlying MNC osmosensitivity are not fully understood. We showed previously that high osmolality activates phospholipase C (PLC) in rat MNCs in a Ca(2+)-dependent manner and th...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Park, Sung Jin, Haan, Kirk D., Nakamura, Yoshikazu, Fukami, Kiyoko, Fisher, Thomas E.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8055080/
https://ncbi.nlm.nih.gov/pubmed/33707294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2892-20.2021
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