ARID1A regulates R-loop associated DNA replication stress

ARID1A is a core DNA-binding subunit of the BAF chromatin remodeling complex, and is lost in up to 7% of all cancers. The frequency of ARID1A loss increases in certain cancer types, such as clear cell ovarian carcinoma where ARID1A protein is lost in about 50% of cases. While the impact of ARID1A lo...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Tsai, Shuhe, Fournier, Louis-Alexandre, Chang, Emily Yun-chia, Wells, James P., Minaker, Sean W., Zhu, Yi Dan, Wang, Alan Ying-Hsu, Wang, Yemin, Huntsman, David G., Stirling, Peter C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8055027/
https://ncbi.nlm.nih.gov/pubmed/33826602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009238
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados