African Americans Have Differences in CSF Soluble TREM2 and Associated Genetic Variants

OBJECTIVE: To evaluate for racial differences in triggering receptor expressed on myeloid cells 2 (TREM2), a key immune mediator in Alzheimer disease, the levels of CSF soluble TREM2 (sTREM2), and the frequency of associated genetic variants were compared in groups of individuals who self-reported t...

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Udgivet i:Neurol Genet
Main Authors: Schindler, Suzanne E., Cruchaga, Carlos, Joseph, Amulya, McCue, Lena, Farias, Fabiana H.G., Wilkins, Consuelo H., Deming, Yuetiva, Henson, Rachel L., Mikesell, Robert J., Piccio, Laura, Llibre-Guerra, Jorge J., Moulder, Krista L., Fagan, Anne M., Ances, Beau M., Benzinger, Tammie L.S., Xiong, Chengjie, Holtzman, David M., Morris, John C.
Format: Artigo
Sprog:Inglês
Udgivet: Wolters Kluwer 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8054965/
https://ncbi.nlm.nih.gov/pubmed/33884297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXG.0000000000000571
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