TP53 mutation and MET amplification in circulating tumor DNA analysis predict disease progression in patients with advanced gastric cancer

BACKGROUND: Gastric cancer (GC) is a heterogeneous disease that encompasses various molecular subtypes. The molecular mutation characteristics of circulating tumor DNA (ctDNA) in advanced gastric cancer (AGC), especially the clinical utility of TP53 mutation and MET amplification in ctDNA need to be...

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Vydáno v:PeerJ
Hlavní autoři: Li, Jia, Li, Zhaoyan, Ding, Yajie, Xu, Yan, Zhu, Xiaohong, Cao, Nida, Huang, Chen, Qin, Mengmeng, Liu, Feng, Zhao, Aiguang
Médium: Artigo
Jazyk:Inglês
Vydáno: PeerJ Inc. 2021
Témata:
Bioinformatics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8054733/
https://ncbi.nlm.nih.gov/pubmed/33959414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.11146
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