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TP53 mutation and MET amplification in circulating tumor DNA analysis predict disease progression in patients with advanced gastric cancer

BACKGROUND: Gastric cancer (GC) is a heterogeneous disease that encompasses various molecular subtypes. The molecular mutation characteristics of circulating tumor DNA (ctDNA) in advanced gastric cancer (AGC), especially the clinical utility of TP53 mutation and MET amplification in ctDNA need to be...

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Detalhes bibliográficos
Publicado no:PeerJ
Main Authors: Li, Jia, Li, Zhaoyan, Ding, Yajie, Xu, Yan, Zhu, Xiaohong, Cao, Nida, Huang, Chen, Qin, Mengmeng, Liu, Feng, Zhao, Aiguang
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8054733/
https://ncbi.nlm.nih.gov/pubmed/33959414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.11146
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