TP53 mutation and MET amplification in circulating tumor DNA analysis predict disease progression in patients with advanced gastric cancer

BACKGROUND: Gastric cancer (GC) is a heterogeneous disease that encompasses various molecular subtypes. The molecular mutation characteristics of circulating tumor DNA (ctDNA) in advanced gastric cancer (AGC), especially the clinical utility of TP53 mutation and MET amplification in ctDNA need to be...

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Udgivet i:PeerJ
Main Authors: Li, Jia, Li, Zhaoyan, Ding, Yajie, Xu, Yan, Zhu, Xiaohong, Cao, Nida, Huang, Chen, Qin, Mengmeng, Liu, Feng, Zhao, Aiguang
Format: Artigo
Sprog:Inglês
Udgivet: PeerJ Inc. 2021
Fag:
Bioinformatics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8054733/
https://ncbi.nlm.nih.gov/pubmed/33959414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.11146
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