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Time-resolved proteomics profiling of the ciliary Hedgehog response

The primary cilium is a signaling compartment that interprets Hedgehog signals through changes of its protein, lipid, and second messenger compositions. Here, we combine proximity labeling of cilia with quantitative mass spectrometry to unbiasedly profile the time-dependent alterations of the ciliar...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: May, Elena A., Kalocsay, Marian, D’Auriac, Inès Galtier, Schuster, Patrick S., Gygi, Steven P., Nachury, Maxence V., Mick, David U.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8054476/
https://ncbi.nlm.nih.gov/pubmed/33856408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202007207
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