Proteomics of Primary Cilia by Proximity Labeling

While cilia are recognized as important signaling organelles, the extent of ciliary functions remains unknown because of difficulties in cataloguing proteins from mammalian primary cilia. We present a method that readily captures rapid snapshots of the ciliary proteome by selectively biotinylating c...

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Pubblicato in:Dev Cell
Autori principali: Mick, David U., Rodrigues, Rachel B., Leib, Ryan D., Adams, Christopher M., Chien, Allis S., Gygi, Steven P., Nachury, Maxence V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662609/
https://ncbi.nlm.nih.gov/pubmed/26585297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2015.10.015
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