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CAR-T cells and BiTEs in solid tumors: challenges and perspectives
Chimeric antigen receptor (CAR)-modified T cells and BiTEs are both immunotherapies which redirect T cell specificity against a tumor-specific antigen through the use of antibody fragments. They demonstrated remarkable efficacy in B cell hematologic malignancies, thus paving the way for their develo...
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| Pubblicato in: | J Hematol Oncol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8054411/ https://ncbi.nlm.nih.gov/pubmed/33874996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-021-01067-5 |
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