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CAR-T cells and BiTEs in solid tumors: challenges and perspectives

Chimeric antigen receptor (CAR)-modified T cells and BiTEs are both immunotherapies which redirect T cell specificity against a tumor-specific antigen through the use of antibody fragments. They demonstrated remarkable efficacy in B cell hematologic malignancies, thus paving the way for their develo...

詳細記述

保存先:
書誌詳細
出版年:J Hematol Oncol
主要な著者: Edeline, Julien, Houot, Roch, Marabelle, Aurélien, Alcantara, Marion
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8054411/
https://ncbi.nlm.nih.gov/pubmed/33874996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-021-01067-5
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