Intention-to-treat analysis may be more conservative than per protocol analysis in antibiotic non-inferiority trials: a systematic review

BACKGROUND: In non-inferiority trials, there is a concern that intention-to-treat (ITT) analysis, by including participants who did not receive the planned interventions, may bias towards making the treatment and control arms look similar and lead to mistaken claims of non-inferiority. In contrast,...

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Dades bibliogràfiques
Publicat a:BMC Med Res Methodol
Autors principals: Bai, Anthony D., Komorowski, Adam S., Lo, Carson K. L., Tandon, Pranav, Li, Xena X., Mokashi, Vaibhav, Cvetkovic, Anna, Findlater, Aidan, Liang, Laurel, Tomlinson, George, Loeb, Mark, Mertz, Dominik
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8054385/
https://ncbi.nlm.nih.gov/pubmed/33874894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-021-01260-7
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