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J-domain proteins promote client relay from Hsp70 during tail-anchored membrane protein targeting
J-domain proteins (JDPs) play essential roles in Hsp70 function by assisting Hsp70 in client trapping and regulating the Hsp70 ATPase cycle. Here, we report that JDPs can further enhance the targeting competence of Hsp70-bound client proteins during tail-anchored protein (TA) biogenesis. In the guid...
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| Опубликовано в: : | J Biol Chem |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2021
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8054193/ https://ncbi.nlm.nih.gov/pubmed/33741343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100546 |
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