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Expression and Purification of the Human Cation-chloride Cotransporter KCC1 from HEK293F Cells for Structural Studies

Cation-chloride cotransporters (CCCs) mediate the coupled, electroneutral symport of cations such as Na(+) and/or K(+) with chloride across membrane. Among CCCs family, K-Cl cotransporters (KCC1-KCC4) extrude intracellular Cl- by the transmembrane K(+) gradient. In humans, these KCCs play vital role...

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Detalles Bibliográficos
Publicado en:Bio Protoc
Main Authors: Liu, Si, Guo, Jiangtao
Formato: Artigo
Idioma:Inglês
Publicado: Bio-Protocol 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8054176/
https://ncbi.nlm.nih.gov/pubmed/33889660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.3966
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