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Structures and an activation mechanism of human potassium-chloride cotransporters

Potassium-chloride cotransporters KCC1 to KCC4 mediate the coupled export of potassium and chloride across the plasma membrane and play important roles in cell volume regulation, auditory system function, and γ-aminobutyric acid (GABA) and glycine-mediated inhibitory neurotransmission. Here, we pres...

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Podrobná bibliografie
Vydáno v:Sci Adv
Hlavní autoři: Xie, Yuan, Chang, Shenghai, Zhao, Cheng, Wang, Feng, Liu, Si, Wang, Jin, Delpire, Eric, Ye, Sheng, Guo, Jiangtao
Médium: Artigo
Jazyk:Inglês
Vydáno: American Association for the Advancement of Science 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7732191/
https://ncbi.nlm.nih.gov/pubmed/33310850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abc5883
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