DNA nuclear targeting sequences for enhanced non-viral gene transfer: An in vitro and in vivo study

An important bottleneck for non-viral gene transfer commonly relates to translocation of nucleic acids into the nuclear compartment of target cells. So-called 3NFs are optimized short nucleotide sequences able to interact with the transcription factor nuclear factor κB (NF-κB), which can enhance the...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Le Guen, Yann T., Pichon, Chantal, Guégan, Philippe, Pluchon, Kévin, Haute, Tanguy, Quemener, Sandrine, Ropars, Juliette, Midoux, Patrick, Le Gall, Tony, Montier, Tristan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2021
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8053784/
https://ncbi.nlm.nih.gov/pubmed/33898102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2021.03.012
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