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Optimizations of In Vitro Mucus and Cell Culture Models to Better Predict In Vivo Gene Transfer in Pathological Lung Respiratory Airways: Cystic Fibrosis as an Example

The respiratory epithelium can be affected by many diseases that could be treated using aerosol gene therapy. Among these, cystic fibrosis (CF) is a lethal inherited disease characterized by airways complications, which determine the life expectancy and the effectiveness of aerosolized treatments. B...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Ghanem, Rosy, Laurent, Véronique, Roquefort, Philippe, Haute, Tanguy, Ramel, Sophie, Le Gall, Tony, Aubry, Thierry, Montier, Tristan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7823756/
https://ncbi.nlm.nih.gov/pubmed/33396283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13010047
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