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Stress relief for cancer immunotherapy: implications for the ER stress response in tumor immunity
The solid tumor microenvironment is replete with factors that present a stress to infiltrating immune cells. Endoplasmic reticulum (ER) stress sensor PKR-like ER kinase (PERK) is primed to sense and respond to the burden of misfolded proteins in the ER lumen induced by cell stressors. PERK has docum...
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| Publicado no: | Cancer Immunol Immunother |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8053671/ https://ncbi.nlm.nih.gov/pubmed/33104836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-020-02740-3 |
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