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Targeting abnormal ER stress responses in tumors: A new approach to cancer immunotherapy
Cancers thrive under adverse conditions and simultaneously inhibit antitumor immunity. We recently found that endoplasmic reticulum (ER) stress responses driven by the IRE1α-XBP1 pathway not only promote cancer cell survival, but also provoke severe dendritic cell (DC) dysfunction in tumors. Targeti...
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| Publicado no: | Oncoimmunology |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4839339/ https://ncbi.nlm.nih.gov/pubmed/27141359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1098802 |
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