Vitamin K antagonist anticoagulant usage is associated with increased incidence and progression of osteoarthritis

OBJECTIVES: Vitamin K is hypothesised to play a role in osteoarthritis (OA) pathogenesis through effects on vitamin K-dependent bone and cartilage proteins, and therefore may represent a modifiable risk factor. A genetic variant in a vitamin K-dependent protein that is an essential inhibitor for car...

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Bibliografiske detaljer
Udgivet i:Ann Rheum Dis
Main Authors: Boer, Cindy G, Szilagyi, Ingrid, Nguyen, N Long, Neogi, Tuhina, Meulenbelt, Ingrid, Ikram, M Arfan, Uitterlinden, André G, Bierma-Zeinstra, Sita, Stricker, Bruno H, van Meurs, Joyce B
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Publishing Group 2021
Fag:
Osteoarthritis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8053344/
https://ncbi.nlm.nih.gov/pubmed/34412027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2020-219483
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