Silencing SHMT2 inhibits the progression of tongue squamous cell carcinoma through cell cycle regulation

BACKGROUND: Serine hydroxymethyltransferase 2 (SHMT2) is a vital metabolic enzyme in one carbon metabolism catalyzing the conversion of serine to glycine, which has been reported to play a crucial role in the progression of tumors. However, its function in tongue squamous cell carcinoma (TSCC) remai...

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Detalles Bibliográficos
Publicado en:Cancer Cell Int
Autores principales: Liao, Yan, Wang, Fang, Zhang, Yadong, Cai, Hongshi, Song, Fan, Hou, Jinsong
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2021
Materias:
Primary Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8052717/
https://ncbi.nlm.nih.gov/pubmed/33863325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-021-01880-5
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