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Association of Sonic Hedgehog with the extracellular matrix requires its zinc-coordination center

BACKGROUND: Sonic Hedgehog (Shh) has a catalytic cleft characteristic for zinc metallopeptidases and has significant sequence similarities with some bacterial peptidoglycan metallopeptidases defining a subgroup within the M15A family that, besides having the characteristic zinc coordination motif, c...

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Publicado en:BMC Mol Cell Biol
Autores principales: Jägers, Carina, Roelink, Henk
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8052667/
https://ncbi.nlm.nih.gov/pubmed/33863273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-021-00359-5
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