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Molecular analysis of cyclin D1 modulators PRKN and FBX4 as candidate tumor suppressors in sporadic parathyroid adenomas

OBJECTIVE: Primary hyperparathyroidism is most often caused by a sporadic single-gland parathyroid adenoma (PTA), a tumor type for which cyclin D1 is the only known and experimentally validated oncoprotein. However, the molecular origins of its frequent overexpression have remained mostly elusive. I...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Endocr Connect
Κύριοι συγγραφείς: Brewer, Kelly, Nip, Isabel, Bellizzi, Justin, Costa-Guda, Jessica, Arnold, Andrew
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Bioscientifica Ltd 2021
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8052572/
https://ncbi.nlm.nih.gov/pubmed/33617468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EC-21-0055
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