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Molecular analysis of cyclin D1 modulators PRKN and FBX4 as candidate tumor suppressors in sporadic parathyroid adenomas

OBJECTIVE: Primary hyperparathyroidism is most often caused by a sporadic single-gland parathyroid adenoma (PTA), a tumor type for which cyclin D1 is the only known and experimentally validated oncoprotein. However, the molecular origins of its frequent overexpression have remained mostly elusive. I...

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Detalhes bibliográficos
Publicado no:Endocr Connect
Main Authors: Brewer, Kelly, Nip, Isabel, Bellizzi, Justin, Costa-Guda, Jessica, Arnold, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: Bioscientifica Ltd 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8052572/
https://ncbi.nlm.nih.gov/pubmed/33617468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EC-21-0055
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