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Inhibition of GABA interneurons in the mPFC is sufficient and necessary for rapid antidepressant responses
Major depressive disorder (MDD) is associated with alterations of GABAergic interneurons, notably somatostatin (Sst) as well as parvalbumin (Pvalb), in cortical brain areas. In addition, the antidepressant effects of rapid acting drugs are thought to occur via inhibition of GABA interneurons. Howeve...
Enregistré dans:
| Publié dans: | Mol Psychiatry |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8052382/ https://ncbi.nlm.nih.gov/pubmed/33070149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-020-00916-y |
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