Defective viral genomes as therapeutic interfering particles against flavivirus infection in mammalian and mosquito hosts

Arthropod-borne viruses pose a major threat to global public health. Thus, innovative strategies for their control and prevention are urgently needed. Here, we exploit the natural capacity of viruses to generate defective viral genomes (DVGs) to their detriment. While DVGs have been described for mo...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Rezelj, Veronica V., Carrau, Lucía, Merwaiss, Fernando, Levi, Laura I., Erazo, Diana, Tran, Quang Dinh, Henrion-Lacritick, Annabelle, Gausson, Valérie, Suzuki, Yasutsugu, Shengjuler, Djoshkun, Meyer, Bjoern, Vallet, Thomas, Weger-Lucarelli, James, Bernhauerová, Veronika, Titievsky, Avi, Sharov, Vadim, Pietropaoli, Stefano, Diaz-Salinas, Marco A., Legros, Vincent, Pardigon, Nathalie, Barba-Spaeth, Giovanna, Brodsky, Leonid, Saleh, Maria-Carla, Vignuzzi, Marco
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2021
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8052367/
https://ncbi.nlm.nih.gov/pubmed/33863888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22341-7
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