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Molecular features of tumor-derived genetic alterations in circulating cell-free DNA in virtue of autopsy analysis

In cancer patients, circulating cell-free DNA (cfDNA) includes tumor-derived DNA (tDNA). cfDNA has been used clinically for non-invasive gene mutation testing. The aim of this study was to characterize the features of the genetic alterations detected in cfDNA. This study included 6 patients with pri...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Koba, Hayato, Kimura, Hideharu, Yoneda, Taro, Sone, Takashi, Ohkura, Noriyuki, Hara, Johsuke, Hosomichi, Kazuyoshi, Tajima, Atsushi, Kasahara, Kazuo
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8052353/
https://ncbi.nlm.nih.gov/pubmed/33863951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-87094-1
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