Selective gene amplification to detect the T790M mutation in plasma from patients with advanced non-small cell lung cancer (NSCLC) who have developed epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) resistance

BACKGROUND: The epidermal growth factor receptor (EGFR) T790M mutation is associated with resistance to EGFR tyrosine kinase inhibitors (EGFR-TKIs) in non-small cell lung cancer (NSCLC). However, tissues for the genotyping of the EGFR T790M mutation can be difficult to obtain in a clinical setting....

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Detalhes bibliográficos
Publicado no:J Thorac Dis
Main Authors: Nishikawa, Shingo, Kimura, Hideharu, Koba, Hayato, Yoneda, Taro, Watanabe, Satoshi, Sakai, Tamami, Hara, Johsuke, Sone, Takashi, Kasahara, Kazuo, Nakao, Shinji
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5906242/
https://ncbi.nlm.nih.gov/pubmed/29707292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jtd.2018.01.144
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