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Avid binding by B cells to the Plasmodium circumsporozoite protein repeat suppresses responses to protective subdominant epitopes
Antibodies targeting the NANP/NVDP repeat domain of the Plasmodium falciparum circumsporozoite protein (CSP(Repeat)) can protect against malaria. However, it has also been suggested that the CSP(Repeat) is a decoy that prevents the immune system from mounting responses against other domains of CSP....
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| 出版年: | Cell Rep |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Cell Press
2021
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8052187/ https://ncbi.nlm.nih.gov/pubmed/33852850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.108996 |
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