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Avid binding by B cells to the Plasmodium circumsporozoite protein repeat suppresses responses to protective subdominant epitopes
Antibodies targeting the NANP/NVDP repeat domain of the Plasmodium falciparum circumsporozoite protein (CSP(Repeat)) can protect against malaria. However, it has also been suggested that the CSP(Repeat) is a decoy that prevents the immune system from mounting responses against other domains of CSP....
Kaydedildi:
| Yayımlandı: | Cell Rep |
|---|---|
| Asıl Yazarlar: | , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Cell Press
2021
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8052187/ https://ncbi.nlm.nih.gov/pubmed/33852850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.108996 |
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