Computer-Aided Drug Discovery Identifies Alkaloid Inhibitors of Parkinson's Disease Associated Protein, Prolyl Oligopeptidase

Parkinson's disease is a common neurodegenerative disorder marked by the accumulation of the protein alpha synuclein. Studies have indicated the role of prolyl oligopeptidase (POP), a serine protease, in alpha synuclein accumulation. Therefore, POP emerges as an attractive medicinal target. Tra...

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Veröffentlicht in:Evid Based Complement Alternat Med
Hauptverfasser: Kulkarni, Apoorva M., Rampogu, Shailima, Lee, Keun Woo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2021
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8052153/
https://ncbi.nlm.nih.gov/pubmed/33897801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/6687572
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