Toll-Like Receptor 4 Mediated Oxidized Low-Density Lipoprotein-Induced Foam Cell Formation in Vascular Smooth Muscle Cells via Src and Sirt1/3 Pathway

Oxidized low-density lipoprotein (oxLDL) induced a foam-cell-like phenotype of the vascular smooth muscle cells (VSMCs), leading to the inflammatory responses incorporating Toll-like receptor- (Tlr-) mediated cellular alterations. However, the role of Tlr4 in foam cell formation and underlying molec...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Chen, Zhongli, Xue, Qiqi, Cao, Lijuan, Wang, Yanpin, Chen, Yuanyuan, Zhang, Xiaojie, Xiao, Fan, Yang, Ying, Hayden, Melvin R., Liu, Yan, Yang, Ke
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2021
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8052139/
https://ncbi.nlm.nih.gov/pubmed/33927570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/6639252
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