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NG2 proteoglycan ablation reduces foam cell formation and atherogenesis via decreased low-density lipoprotein retention by synthetic smooth muscle cells
OBJECTIVES: Obesity and hyperlipidemia are critical risk factors for atherosclerosis. Since ablation of NG2 proteoglycan in mice leads to hyperlipidemia and obesity, we investigated the impact of NG2 ablation on atherosclerosis in ApoE null mice. APPROACH AND RESULTS: Immunostaining indicates that N...
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| Publicado no: | Arterioscler Thromb Vasc Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4690796/ https://ncbi.nlm.nih.gov/pubmed/26543095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.306074 |
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