NG2 proteoglycan ablation reduces foam cell formation and atherogenesis via decreased low-density lipoprotein retention by synthetic smooth muscle cells

OBJECTIVES: Obesity and hyperlipidemia are critical risk factors for atherosclerosis. Since ablation of NG2 proteoglycan in mice leads to hyperlipidemia and obesity, we investigated the impact of NG2 ablation on atherosclerosis in ApoE null mice. APPROACH AND RESULTS: Immunostaining indicates that N...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Arterioscler Thromb Vasc Biol
Hlavní autoři: She, Zhi-Gang, Chang, Yunchao, Pang, Hong-Bo, Han, Wenlong, Chen, Hou-Zao, Smith, Jeffrey W., Stallcup, William B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690796/
https://ncbi.nlm.nih.gov/pubmed/26543095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.306074
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky