Mixed chimerism and acceptance of kidney transplants after immunosuppressive drug withdrawal

Preclinical studies have shown that persistent mixed chimerism is linked to acceptance of organ allografts without immunosuppressive (IS) drugs. Mixed chimerism refers to continued mixing of donor and recipient hematopoietic cells in recipient tissues after transplantation of donor cells. To determi...

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Udgivet i:Sci Transl Med
Main Authors: Busque, Stephan, Scandling, John D., Lowsky, Robert, Shizuru, Judith, Jensen, Kent, Waters, Jeffrey, Wu, Hsin-Hsu, Sheehan, Kevin, Shori, Asha, Choi, Okmi, Pham, Thomas, Fernandez Vina, Marcelo A., Hoppe, Richard, Tamaresis, John, Lavori, Philip, Engleman, Edgar G., Meyer, Everett, Strober, Samuel
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8051148/
https://ncbi.nlm.nih.gov/pubmed/31996467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aax8863
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