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Mixed chimerism and acceptance of kidney transplants after immunosuppressive drug withdrawal

Preclinical studies have shown that persistent mixed chimerism is linked to acceptance of organ allografts without immunosuppressive (IS) drugs. Mixed chimerism refers to continued mixing of donor and recipient hematopoietic cells in recipient tissues after transplantation of donor cells. To determi...

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Publicado en:Sci Transl Med
Autores principales: Busque, Stephan, Scandling, John D., Lowsky, Robert, Shizuru, Judith, Jensen, Kent, Waters, Jeffrey, Wu, Hsin-Hsu, Sheehan, Kevin, Shori, Asha, Choi, Okmi, Pham, Thomas, Fernandez Vina, Marcelo A., Hoppe, Richard, Tamaresis, John, Lavori, Philip, Engleman, Edgar G., Meyer, Everett, Strober, Samuel
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8051148/
https://ncbi.nlm.nih.gov/pubmed/31996467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aax8863
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