Sec62 promotes stemness and chemoresistance of human colorectal cancer through activating Wnt/β-catenin pathway

BACKGROUND: Cancer stem cell (CSC)-related chemoresistance leads to poor outcome of the patients with colorectal cancer (CRC). In this study, we identified the chemoresistance-relevant molecules and decipher the involved mechanisms to provide potential therapeutic target for CRC. We focused on Sec62...

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Dades bibliogràfiques
Publicat a:J Exp Clin Cancer Res
Autors principals: Liu, Xiaofeng, Su, Kunqi, Sun, Xiaoyan, Jiang, Yang, Wang, Lijun, Hu, Chenyu, Zhang, Chunfeng, Lu, Min, Du, Xiaojuan, Xing, Baocai
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8051072/
https://ncbi.nlm.nih.gov/pubmed/33858476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-01934-6
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