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Free fatty acid binding pocket in the locked structure of SARS-CoV-2 spike protein

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), represents a global crisis. Key to SARS-CoV-2 therapeutic development is unraveling the mechanisms that drive high infectivity, broad tissue tropism, and severe pathology. Our 2.85-angstrom c...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Toelzer, Christine, Gupta, Kapil, Yadav, Sathish K. N., Borucu, Ufuk, Davidson, Andrew D., Kavanagh Williamson, Maia, Shoemark, Deborah K., Garzoni, Frederic, Staufer, Oskar, Milligan, Rachel, Capin, Julien, Mulholland, Adrian J., Spatz, Joachim, Fitzgerald, Daniel, Berger, Imre, Schaffitzel, Christiane
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8050947/
https://ncbi.nlm.nih.gov/pubmed/32958580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abd3255
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